The Study of Vitamins B1, B6, and B12 Effects on Adrenal Cortex Adaptation by Monitoring Some Enzyme Systems in Rats Trained by Swimming

The adrenal hormones play a central role in response to environmental stimuli, both internal and external. We analyzed enzymes activities (LDHlactate dehydrogenase, GLDHglutamate dehydrogenase and AcPh – acid phosphatase) in adrenal cortex through swimming exercises and under the influence of B-group vitamins. The analyzed cases in the experiment revealed significant increase of enzyme activities, namely in the zona fasciculata and zona reticularis of the adrenal cortex. Physical exertion is a form of stress and causes steroidogenesis process expression. The vitamins used take part as co-ferments in production of a lot of enzymes and in their activities as well. Improvement of the enzyme system in adrenal glands in animals through swimming training with addition of vitamins B1, B6 and B12 leads to faster and long-term production of hormones necessary for stress response known as General Adaptation Syndrome. Acta Medica Medianae 2014;53(2):33-39.